HCID 57464096, compound → HCID 57455394, compound

Participants

Reaction Steps

The preparation of 4-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)butyraldehyde is described in parts A-C of Example 6. The general procedure of Part G of Example 4 was repeated using 4-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)butyraldehyde (6.4 g, 22.74 mmol) in lieu of 4-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)-N-methoxy-N-methylbutanamide to provide 5.2 g of 5-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)pentan-2-ol as a tan oil.

Provenance & Evidence