HCID 69000656, compound → HCID 69507300, compound

Participants

Reaction Steps

Crude 4-[(5,6-dimethyl-8-nitrotetraazolo[1,5-a]pyridin-7-yl)amino]butan-1-ol was combined in a pressure vessel with catalyst (1.3 g of 5% platinum on carbon), and acetonitrile (222 mL). The reaction mixture was placed under hydrogen pressure (30 psi, 2.1×105 Pa) for 3 hours, filtered through a layer of CELITE filter aid, and the filter cake was washed with methanol. The filtrate was concentrated under reduced pressure to provide 11.15 g of 4-[(8-amino-5,6-dimethyl-tetrazolo[1,5-a]pyridin-7-yl)amino]butan-1-ol.

Provenance & Evidence