HCID 57455389, compound → HCID 69507057, compound

Participants

Reaction Steps

A modified version of the general methods described in Parts D-G of Example 4 was sequentially followed with ethyl 4-(2-propyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butyrate (6.0 g, 18.4 mmol) used in lieu of ethyl 4-(2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butyrate as the starting substrate. Isolation after the last step of the sequence afforded 6.06 g of crude 5-(2-propyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)pentan-2-one.

Provenance & Evidence