反应详情

85 ml of 30% strength hydrogen peroxide solution are added to a solution of 5-amino-1-cyclopentyl-1H-pyrazole-4-carbonitrile (6.74 g, 38.3 mmol) in a mixture of 300 ml of ethanol and 371 ml of concentrated aqueous ammonia solution at room temperature and stirred at room temperature overnight. The nonaqueous solvents are then stripped off in a rotary evaporator. The product precipitates as solid from the remaining mixture and is filtered off with suction, washed with diethyl ether and dried under high vacuum.

1. customThe nonaqueous solvents are then stripped off in a rotary evaporator
2. customThe product precipitates as solid from the remaining mixture
3. filtrationis filtered off with suction
4. washwashed with diethyl ether
5. customdried under high vacuum