Sodium Hydroxide → HCID 10773402, compound

Participants

Reaction Steps

28.2 g of 2-acetoxymethyl-3-methyl-4-ethoxy-pyridine was added dropwise to a 25% aqueous solution of sodium hydroxide, and the mixture was allowed to react for one hour at room temperature. Subsequently, the reaction liquid was diluted with toluene, and then the toluene phase was washed with water, dried over anhydrous magnesium sulfate, and then concentrated to dryness, to obtain 10.7 g of 2-hydroxymethyl-3-methyl-4-ethoxy-pyridine as an oily matter.

Provenance & Evidence