Sodium Hydroxide → HCID 68467548, compound

Participants

Reaction Steps

22.0 g (0.088 mol, 1.0 eq.) of 4-pentyloxy-2-acetoxymethyl-3-methylpyridine was added dropwise to a 25% aqueous solution of sodium hydroxide, and the mixture was allowed to react for one hour at room temperature. Subsequently, the reaction liquid was diluted with toluene, and then the toluene phase was washed with water, dried over anhydrous magnesium sulfate, and then concentrated to dryness, to obtain 11.2 g of 4-pentyloxy-2-hydroxymethyl-3-methylpyridine as an oily matter (yield 60.8%).

Provenance & Evidence