Sodium Hydroxide → HCID 68468227, compound

Participants

Reaction Steps

17.3 g (0.065 mol, 1.0 eq.) of 4-hexyloxy-2-acetoxymethyl-3-methylpyridine was added dropwise to a 25% aqueous solution of sodium hydroxide at 5 to 22° C., and the mixture was allowed to react for one hour at room temperature, and then extracted with chloroform. The extract was washed with water, dried over anhydrous magnesium sulfate, and then concentrated to dryness, to obtain 12.7 g of 4-hexyloxy-2-hydroxymethyl-3-methylpyridine as a brown oily matter (yield 87.6%).

Provenance & Evidence