Sodium Hydroxide → HCID 68468934, compound

Participants

Reaction Steps

17.3 g (0.059 mol, 1.0 eq.) of 4-octyloxy-2-acetoxymethyl-3-methylpyridine was added dropwise to a 25% aqueous solution of sodium hydroxide at 11 to 22° C., and the mixture was allowed to react for one hour at room temperature, and then extracted with chloroform. The extract was washed with water, dried over magnesium sulfate, and then concentrated to dryness, to obtain 12.2 g of 4-octyloxy-2-hydroxymethyl-3-methylpyridine as a pale brown oily matter (yield 82.3%).

Provenance & Evidence