Lithium Hydroxide → HCID 23069970, compound

Participants

Reaction Steps

To a stirred solution of methyl 5-cyano-2-[(phenylmethyl)oxy]benzoate (may be prepared as described in Description 13; 200 mg, 0.75 mmol) in THF (2 ml) was added a solution of lithium hydroxide (94 mg, 2.25 mmol) in water (8 ml). The reaction mixture was stirred at room temperature overnight. The THF was removed and the mixture was adjusted to pH 7 with 2N HCl. The mixture was filtered and the residue dried to yield the title compound as a yellow solid. 160 mg.

Provenance & Evidence