Hydrochloric Acid → HCID 68108650, compound

Participants

Reaction Steps

A solution of LiOH (393 mg, 9.36 mmol) in water (10 ml) was added to a stirred solution of methyl 5-[(4-methyl-1-piperazinyl)carbonyl]-2-[(phenylmethyl)oxy]benzoate (may be prepared as described in Description 50; 345 mg, 0.94 mmol) in tetrahydrofuran (2.5 ml) at room temperature. The mixture was stirred at room temperature for 3 h. The mixture was acidified by HCl (6 mol/L). The solvent was evaporated in vacuo to afford the crude product. The crude product was used directly in the next step without further purification.

Provenance & Evidence