HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 24804226, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | HCID 24804064 | HCID 24804064 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 24804226 | HCID 24804226 | — |
Reaction Steps
N-(Cycloheptylmethyl)-2-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-1-oxo-1,2-dihydroisoquinoline-5-carboxamide (110 mg, 0.00028 mol), hydrogen chloride (5 mL, 0.006 mol) as 2M solution in ether and methylene chloride (5 mL, 0.08 mol) were stirred at room temperature for 2 hours. The volatiles were removed under vacuum, the residue was purified via flash chromatography (12 g of silica gel, 0-10% MeOH/CH2Cl2) to give a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08779144B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-dfebe55bd22b421ca74830cd3a0c13de |
| Source note | uspto-grants-2014_07 |