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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1624990Generated: November 2, 2026

Hydrochloric Acid → HCID 24804226, compound

https://huagongshe.com/reaction/1624990

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantHCID 24804064HCID 24804064—
SolventDiethyl EtherHCID 3283—
ProductHCID 24804226HCID 24804226—

Reaction Steps

N-(Cycloheptylmethyl)-2-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-1-oxo-1,2-dihydroisoquinoline-5-carboxamide (110 mg, 0.00028 mol), hydrogen chloride (5 mL, 0.006 mol) as 2M solution in ether and methylene chloride (5 mL, 0.08 mol) were stirred at room temperature for 2 hours. The volatiles were removed under vacuum, the residue was purified via flash chromatography (12 g of silica gel, 0-10% MeOH/CH2Cl2) to give a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08779144B2
Source datasetuspto-grants-2014_07
ORD IDord-dfebe55bd22b421ca74830cd3a0c13de
Source noteuspto-grants-2014_07