Phosphoric Acid → HCID 178434041, compound

Participants

Reaction Steps

Maraviroc (100 gm) was dissolved in ethanol (100 ml) and stirred for 30 minutes at room temperature. To the solution was added phosphoric acid (2 gm) and then cooled to 0 to 5° C. The reaction mass was stirred for 12 hours at 0 to 5° C. and filtered. The solid obtained was dried to obtain 98 gm of crystalline form 4 of maraviroc phosphate.

Provenance & Evidence