Water → 2-(2,4,5-Trimethoxyphenyl)propanal

HRID 1625187Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1625187
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[C:6]([O:11][CH3:12])=[CH:5][C:4]=1[CH:13]=[CH:14]C.BrN1[C:21](=[O:22])CCC1=O.O>[Br-].C([N+](C)(C)C)CCCCCCCCCCCCCCC.CS(C)=O>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[C:6]([O:11][CH3:12])=[CH:5][C:4]=1[CH:13]([CH3:14])[CH:21]=[O:22]

Komponenten

6

Edukt 3

HCID 962WaterHCID 179031,2,4-Trimethoxy-5-(1-propenyl)benzeneHCID 67184N-bromobutanimide

Produkt 1

HCID 468963042-(2,4,5-Trimethoxyphenyl)propanalAusbeute 45 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 5974Hexadecyltrimethylammonium BromideKatalysatorHCID 679Dimethyl SulfoxideLösungsmittel

Versuchsvorschrift

A mixture of 2,4,5 trimethoxy phenyl propene (1 mmol), N-bromosuccinimide (1.5 mmol), water (12 ml), DMSO (3 ml), cetyltrimethyl ammonium bromide (0.3 mmol) was taken in a 100 ml Erlenmeyer flask fitted with loose funnel at the top. The flask was shaken well and placed inside the multimode microwave oven and irradiated (900 W) for 8 minutes in parts. After completion of reaction, the reaction mixture was worked up as in example-1 to provide the corresponding 2-(2,4,5 trimethoxy phenyl)propionaldehyde (45% yield) whose spectral data matched with that mentioned in example-1.

Aufarbeitung

  1. customfitted with loose funnel at the top
  2. customirradiated (900 W) for 8 minutes in parts
  3. customAfter completion of reaction

Quellen und Nachweise

ORD-Eintrag
ord-3ff7a2235fe242b68468fde3be945119
Quelldatensatz
uspto-grants-2014_07
Patentnummer
US08779200B2

Notizen zur Reaktion

Wird geladen…