m-Chloroperbenzoic acid → HCID 178526242, compound

HRID 1625205Notes

Reaction equation

HRID 1625205 reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]1[C:11]2[C:6](=[N:7][CH:8]=[CH:9][CH:10]=2)[NH:5][N:4]=1.ClC1C=C(C=CC=1)C(OO)=[O:19]>COCCOC.CCCCCCC>[F:13][C:2]([F:1])([F:12])[C:3]1[C:11]2[C:6](=[N+:7]([O-:19])[CH:8]=[CH:9][CH:10]=2)[NH:5][N:4]=1

Participants

5

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 178506292HCID 178506292, compound

Product 1

HCID 178526242HCID 178526242, compoundYield 96%

Reagents, catalysts & solvents 2

HCID 80711,2-DimethoxyethaneSolventHCID 8900HeptaneSolvent

Procedure

Compound (1a) was dissolved in ethylene glycol dimethyl ether (100 mL) and heptane (200 mL), and m-chloroperoxybenzoic acid (33.9 g) was added to the resulting solution at 0° C., followed by stirring at room temperature for 1 hr. The precipitate was collected by filtration to obtain compound (1b) (33.3 g, 96%) as a white solid.

Workup

  1. filtrationThe precipitate was collected by filtration

Sources & evidence

ORD record
ord-037d1885348b42d3b15871185524f3d0
Source dataset
uspto-grants-2014_07
Patent number
US08779142B2

Reaction notes

Loading…