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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1625443Generated: November 1, 2026

Trifluoroacetic acid → HCID 68606710, compound

https://huagongshe.com/reaction/1625443

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 59362379HCID 59362379—
SolventDichloromethaneHCID 6344—
ProductHCID 68606710HCID 68606710—

Reaction Steps

Into a vial was dissolved (1-benzenesulfonyl-3-[3-({[1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carbonyl]-amino}-methyl)-phenyl]-1H-pyrrolo[2,3-b]pyridin-5-ylmethyl}-carbamic acid tert-butyl ester (0.259 mmol) in methylene chloride (2.00 mL, Acros) and trifluoroacetic acid (2.00 mL, 0.0260 mol; Acros). The reaction was stirred for 30 min, then the reaction was evaporated to dryness to give the crude amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08778977B2
Source datasetuspto-grants-2014_07
ORD IDord-d0731e5f0a1046a982a906352af8c4cc
Source noteuspto-grants-2014_07