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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1625863Generated: November 3, 2026

Benzene, 1-bromo-4-(trifluoromethyl)- → 2-[4-(Trifluoromethyl)phenyl]thiophene

https://huagongshe.com/reaction/1625863

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-bromo-4-(trifluoromethyl)-HCID 67872—
Reactant2-Thiopheneboronic acidHCID 2733960—
Product2-[4-(Trifluoromethyl)phenyl]thiopheneHCID 12168056—

Reaction Steps

4-Bromobenzotrifluoride and thiophene-2-boronic acid were treated in a manner similar to Reference Example 20-(1) to give 2-(4-trifluoromethylphenyl)thiophene as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08785403B2
Source datasetuspto-grants-2014_07
ORD IDord-b01eff160c10402982aa9c7a62ef7f79
Source noteuspto-grants-2014_07