HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(5-Bromo-2-chlorophenyl)acetic acid → 5-Bromo-2-chloro-1-(2-(5-phenyl-2-thienyl)ethyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(5-Bromo-2-chlorophenyl)acetic acid | HCID 15512441 | — |
| Reactant | (2S,3R,4R,5S,6R)-2-[3-[(5-ethylthiophen-2-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | HCID 46930338 | — |
| Product | 5-Bromo-2-chloro-1-(2-(5-phenyl-2-thienyl)ethyl)benzene | HCID 66607744 | — |
Reaction Steps
The above 5-bromo-2-chlorophenylacetic acid was treated in a manner similar to Reference Example 118-(4) and (5) to give the desired 5-bromo-2-chloro-1-(2-(5-phenyl-2-thienyl)ethyl)benzene as a pale yellow solid. APCI-Mass m/Z 377/379 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785403B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-50b8f3cc947e41ffa4637d97cefe899e |
| Source note | uspto-grants-2014_07 |