HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Xylene → HCID 67078397, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Xylene | HCID 7237 | — |
| Reactant | Ethyl 2-oxocyclohexanecarboxylate | HCID 95543 | — |
| Reactant | 5-Bromopyridine-2,3-diamine | HCID 691156 | — |
| Product | HCID 67078397 | HCID 67078397 | — |
Reaction Steps
2,3-Diamino-5-bromopyridine (50 g) and 2-cyclohexanonecarboxylic acid ethyl ester (63.5 ml) were heated under reflux in xylene (2000 ml) for 64 hours. The reaction solution was cooled to room temperature and the precipitated crystals were collected by filtration. The resulting crude crystals were recrystallized from toluene to give the title compound (30 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785438B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-ab878942854a464fa73ff5998127cd52 |
| Source note | uspto-grants-2014_07 |