HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanamine, N-methoxy-, hydrochloride (1:1) → HCID 58082769, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanamine, N-methoxy-, hydrochloride (1:1) | HCID 81138 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | 2-methyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxylic Acid | HCID 2775651 | — |
| Product | HCID 58082769 | HCID 58082769 | 92% |
Reaction Steps
In a manner analogous to that described in Example 1 d), the condensation of 2-methyl-5-trifluoromethyl-oxazole-4-carboxylic acid and N,O-dimethylhydroxylamine hydrochloride by N-(3-dimethylaminopropyl)-N′-ethyl-carbodiimide hydrochloride yielded the title compound (92% yield) as a colorless oil. MS (ISP): m/z=239.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785436B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-a433e4436c4e4c29a6a89899412d62e1 |
| Source note | uspto-grants-2014_07 |