Iodine → HCID 87410559, compound

Participants

Reaction Steps

Commercially available 2-Trifluoromethylphenothiazine (1.14 g, 4.28 mmol) was dissolved in CHCl3 (20 mL) and a solution of I2 (3.25 g, 12.84 mmol) in CHCl3 (120 mL) was added. The mixture was warmed at 55° C. to 60° C. until the SM was consumed (by TLC). The reaction mixture was allowed to cool to RT and the solvent was evaporated. The residue was stirred in Et2O, filtered off and washed with Et2O until the filtrate was colorless. The intermediate was used without further purification.

Provenance & Evidence