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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1626265Generated: October 31, 2026

1-Methylpiperazine → HCID 178436997, compound

https://huagongshe.com/reaction/1626265

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant1-Ethyl-9-methylphenothiazin-5-ium tetraiodide hydrateHCID 86667030—
SolventMethanolHCID 887—
ProductHCID 178436997HCID 178436997—

Reaction Steps

A solution of 1-ethyl-9-methylphenothiazin-5-ium tetraiodide hydrate (50 mg, 0.07 mmol) in methanol (10 mL) and 1-methylpiperazine (30 mg, 0.3 mmol) was stirred for 2 h at room temperature. The resulting mixture was concentrated to dryness and purified by flash chromatography using the methanol-chloroform gradient to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08785434B2
Source datasetuspto-grants-2014_07
ORD IDord-c08096aee9514845a0d8d3545066df5a
Source noteuspto-grants-2014_07