Chloroform → HCID 178436732, compound

HRID 1626268Notes

Reaction equation

HRID 1626268 reaction equation
O.[I-:2].[I-].[I-].[I-].[CH2:6]([C:8]1[CH:9]=[CH:10][CH:11]=[C:12]2[C:21]=1[N:20]=[C:19]1[C:14]([CH:15]=[CH:16][CH:17]=[C:18]1[CH3:22])=[S+:13]2)[CH3:7].[CH2:23]([C:25]1[CH:26]=[CH:27][CH:28]=[C:29]2[C:38]=1[N:37]=[C:36]1[C:31]([CH:32]=[CH:33][CH:34]=[C:35]1[CH3:39])=[S+:30]2)[CH3:24].[CH2:40]([C:42]1[CH:43]=[CH:44][CH:45]=[C:46]2[C:55]=1[N:54]=[C:53]1[C:48]([CH:49]=[CH:50][CH:51]=[C:52]1[CH3:56])=[S+:47]2)[CH3:41].C(C1C=CC=[C:63]2[C:72]=1[N:71]=[C:70]1[C:65](C=CC=C1C)=[S+]2)C.C(Cl)(Cl)Cl>>[I-:2].[I-:2].[I-:2].[CH2:6]([C:8]1[C:21]2[C:12](=[S+:13][C:14]3[C:19]([N:20]=2)=[C:18]([CH3:22])[CH:17]=[CH:16][CH:15]=3)[CH:11]=[C:10]([N:37]2[CH2:36][CH2:31][CH2:29][CH2:38]2)[CH:9]=1)[CH3:7].[CH2:40]([C:42]1[C:55]2[C:46](=[S+:47][C:48]3[C:53]([N:54]=2)=[C:52]([CH3:56])[CH:51]=[CH:50][CH:49]=3)[CH:45]=[C:44]([N:71]2[CH2:70][CH2:65][CH2:63][CH2:72]2)[CH:43]=1)[CH3:41].[CH2:23]([C:25]1[C:38]2[C:29](=[S+:30][C:31]3[C:36]([N:37]=2)=[C:35]([CH3:39])[CH:34]=[CH:33][CH:32]=3)[CH:28]=[C:27]([N:20]2[CH2:19][CH2:14][CH2:12][CH2:21]2)[CH:26]=1)[CH3:24]

Participants

3

Reactant 2

HCID 6212ChloroformHCID 866670301-Ethyl-9-methylphenothiazin-5-ium tetraiodide hydrate

Product 1

HCID 178436732HCID 178436732, compound

Procedure

To the stirred mixture of 9-ethyl-1-methylphenothiazin-5-ium tetraiodide hydrate (383 mg, 0.5 mmol) in anhydrous CHCl3 (20 mL) pyrrolidine (71 mg, 1.0 mmol) was added drop wise over 4 h. The resulting mixture was stirred at room temperature overnight and concentrated to dryness.

Workup

  1. additionwas added drop wise over 4 h
  2. concentrationconcentrated to dryness

Sources & evidence

ORD record
ord-30a50646906a41dea6dadf3bd6469473
Source dataset
uspto-grants-2014_07
Patent number
US08785434B2

Reaction notes

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