Sodium Hydroxide → HCID 86664397, compound

Participants

Reaction Steps

2-phenyloxazole-4-carbaldehyde (5.0 g, 28.9 mmol) and 2.0 M aqueous sodium hydroxide solution (50 ml) were heated to 70° C. in a 250 mL Erlenmeyer flask until dissolved. Some insoluble dark material remained which was removed by filtration. The reaction was cooled in an ice bath and acidified (sulfuric acid) with swirling. The resulting solid was collected by filtration, washed with water, and dried under vacuum to provide the title compound (4.85 g, 88%).

Provenance & Evidence