4-Fluoroaniline → (S)-1-(4-fluorophenyl)-3-(4-(6-methyl-4-(3-methylmorpholino)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl)phenyl)urea

Participants

Role	Name	HCID	Charge
Reactant	4-Fluoroaniline	HCID 9731	—
Reactant	(S)-phenyl 4-(6-methyl-4-(3-methylmorpholino)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl)phenylcarbamate	HCID 66678768	—
Product	(S)-1-(4-fluorophenyl)-3-(4-(6-methyl-4-(3-methylmorpholino)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl)phenyl)urea	HCID 46912596	—

Method as described for example 51 using intermediate 10 and 4-fluoroaniline as starting materials. Purified by prep. LCMS (high pH).