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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1626567Generated: October 31, 2026

3-Methoxypropylamine → (S)-1-(3-methoxypropyl)-3-(4-(6-methyl-4-(3-methylmorpholino)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl)phenyl)urea

https://huagongshe.com/reaction/1626567

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxypropylamineHCID 1672—
Reactant(S)-phenyl 4-(6-methyl-4-(3-methylmorpholino)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl)phenylcarbamateHCID 66678768—
Product(S)-1-(3-methoxypropyl)-3-(4-(6-methyl-4-(3-methylmorpholino)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl)phenyl)ureaHCID 46912597—

Reaction Steps

Method as described for example 51 using intermediate 10 and 3-methoxypropylamine as starting materials. Purified by prep. LCMS (high pH).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08785457B2
Source datasetuspto-grants-2014_07
ORD IDord-470cf0918483407396d12b03fd8400b6
Source noteuspto-grants-2014_07