Hydrochloric Acid → HCID 66679852, compound

Participants

Reaction Steps

5 mL of THF and 0.65 mL of 1N aqueous sodium hydroxide solution were added to 110 mg (0.35 mmol) of ethyl [3-(adamantan-1-yl)phenoxy]acetate at room temperature, and the mixture was stirred for 6 hours. 1N hydrochloric acid was added to acidify the reaction mixture, and water was added. The precipitated solids were collected by filtration, washed with water, and air-dried, thereby giving 90 mg of [3-(adamantan-1-yl)phenoxy]acetic acid (yield: 89%).

Provenance & Evidence