HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-amino-5-chlorobenzoate → HCID 66680793, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-amino-5-chlorobenzoate | HCID 78878 | — |
| Reactant | 5-(4-Fluorophenyl)thiophene-2-carboxylic acid | HCID 1873401 | — |
| Product | HCID 66680793 | HCID 66680793 | 47% |
Reaction Steps
Using the same method as in Example 3-(i), methyl 5-chloro-2-({[5-(4-fluorophenyl)thiophen-2-yl]carbonyl}amino)benzoate was obtained using 5-(4-fluorophenyl)thiophen-2-carboxylic acid and methyl 2-amino-5-chlorobenzoate. Thereafter, using the same method as in Example 3-(ii), the target 5-chloro-2-({[5-(4-fluorophenyl)thiophen-2-yl]carbonyl}amino)benzoic acid was obtained (yield: 47%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785473B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-5e9fc09de4824a1a8dcd9c7cca32fb85 |
| Source note | uspto-grants-2014_07 |