HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-4-iodobenzene → HCID 68193214, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-4-iodobenzene | HCID 11522 | — |
| Reactant | Methyl 4-bromo-3-methylbenzoate | HCID 3294148 | — |
| Product | HCID 68193214 | HCID 68193214 | 23% |
Reaction Steps
In accordance with Example 19-(2), but using methyl 4-bromo-3-methylbenzoate instead of tert-Butyl 5-(benzyloxy)-2-{[1-(5-bromopyridin-2-yl)piperidin-4-yl]methyl}-6-methylpyrimidine-4-carboxylate, and 1-bromo-4-iodobenzene instead of tert-butyl[(4-iodobenzyl)oxy]dimethylsilane, the title compound (yield 23%) was afforded as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785462B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-2e20adcc2caa415ba3f4e30668feaf08 |
| Source note | uspto-grants-2014_07 |