Dimethylformamide dimethyl acetal → 2-[3-(Dimethylamino)-1-methoxy-2-propenylidene]malononitrile

Participants

Reaction Steps

To a mixture of D1 (34 g, 250 mmol) in methanol (300 ml) was added N,N-dimethylformamide dimethyl acetal (44.68 g, 375 mmol). The reaction mixture was heated at reflux for 2 h. The mixture was then cooled to room temperature and a dark red solid precipitated upon cooling. The solid was filtered off, washed with cold methanol and dried in vacuo yielding compound D2 (16.2 g, 38%) as a red solid.

Provenance & Evidence