反应详情

To a mixture of D1 (34 g, 250 mmol) in methanol (300 ml) was added N,N-dimethylformamide dimethyl acetal (44.68 g, 375 mmol). The reaction mixture was heated at reflux for 2 h. The mixture was then cooled to room temperature and a dark red solid precipitated upon cooling. The solid was filtered off, washed with cold methanol and dried in vacuo yielding compound D2 (16.2 g, 38%) as a red solid.

1. temperatureThe reaction mixture was heated
2. temperatureat reflux for 2 h
3. customa dark red solid precipitated
4. temperatureupon cooling
5. filtrationThe solid was filtered off
6. washwashed with cold methanol
7. customdried in vacuo