TIBA cyclohexane → 2,3,5-Triiodobenzoic acid

HRID 1627243Notes

Reaction equation

HRID 1627243 reaction equation
[CH:1]1[C:6]([I:7])=[C:5]([I:8])[C:4]([C:9]([OH:11])=[O:10])=[CH:3][C:2]=1[I:12].C1CCCCC1>C1(C)C=CC=CC=1>[CH:1]1[C:6]([I:7])=[C:5]([I:8])[C:4]([C:9]([OH:11])=[O:10])=[CH:3][C:2]=1[I:12]

Participants

3

Reactant 1

HCID 131728537TIBA cyclohexane

Product 1

HCID 69482,3,5-Triiodobenzoic acid

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

18.2 mL of TIBA/cyclohexane solution (99 g/L) were mixed with 3.8 mL of MAO/toluene solution to obtain a MAO/TIBA molar ratio of 2:1. The solution was stirred for 1 h at room temperature and transferred into a 50 mL Schlenk flask containing A-1 (37.3 mg, 45.4 μmol). The final solution was diluted with 35.9 mL of cyclohexane. Final mixture concentration=50 gTOT/L and 0.645 gmetallocene/L; color=orange solution.

Sources & evidence

ORD record
ord-b51408bc6b18401687468e12660fcf25
Source dataset
uspto-grants-2014_07
Patent number
US08785575B2

Reaction notes

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