Hydroxylamine → HCID 11588872, compound

Participants

Reaction Conditions

Reaction Steps

The above prepared solution of (E)-3-[1-(5-Pyridin-2-yl-thiophene-2-sulfonyl)-1H-pyrrol-3-yl]-acryloyl chloride hydrochloride was added to an aqueous hydroxylamine solution (50%, 150 g, 2.27 mop at 20-25° C. over a period of 45 min. After stirring for 65 min, water (300 mL) was added and cooled to 0° C. The suspension was filtered and the filter cake was washed with water (150 mL). The title compound was obtained as beige solid (17.3 g).

Provenance & Evidence