Methyl vinyl ketone → HCID 53342911, compound

HRID 1627946Notes

Reaction equation

HRID 1627946 reaction equation
[C:1]([Si:5]([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15][CH:16]=[CH2:17])([CH3:7])[CH3:6])([CH3:4])([CH3:3])[CH3:2].[CH:18]([C:20](C)=[O:21])=C>>[Si:5]([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15]/[CH:16]=[CH:17]/[C:20](=[O:21])[CH3:18])([C:1]([CH3:4])([CH3:3])[CH3:2])([CH3:7])[CH3:6]

Participants

3

Reactant 2

HCID 6570Methyl vinyl ketoneHCID 11482047HCID 11482047, compound

Product 1

HCID 53342911HCID 53342911, compoundYield 74%

Procedure

The representative procedure was followed using tert-butyl(2-allylphenoxy)dimethylsilane (124 mg, 0.50 mmol), methyl vinyl ketone (106 mg, 1.50 mmol) and Grubbs-2 catalyst (8.5 mg, 0.01 mmol). Column chromatography on silica gel (eluting with 3% EtOAc/hexanes) afforded the product as a colorless oil (107 mg, 74%).

Sources & evidence

ORD record
ord-74608cf3920340f1a17167220eb34ebb
Source dataset
uspto-grants-2014_07
Patent number
US08785665B2

Reaction notes

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