N-methyl-2-pyrrolidone → 4-Fluoro-2-(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)benzonitrile

HRID 162802Notes

Reaction equation

HRID 162802 reaction equation
[Br:1][c:2]1[c:3](-[n:9]2[n:10][cH:11][n:12]([CH3:15])[c:13]2=[O:14])[cH:4][c:5]([F:8])[cH:6][cH:7]1.[CH3:19][N:20]1[CH2:21][CH2:22][CH2:23][C:24]1=[O:25].[Cu:16][C:17]#[N:18]>>[c:2]1([C:17]#[N:18])[c:3](-[n:9]2[n:10][cH:11][n:12]([CH3:15])[c:13]2=[O:14])[cH:4][c:5]([F:8])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 13387N-methyl-2-pyrrolidoneHCID 588778431-(2-Bromo-5-fluorophenyl)-4-methyl-1H-1,2,4-triazol-5(4H)-oneHCID 178418546HCID 178418546, compound

Product 1

HCID 588779024-Fluoro-2-(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)benzonitrile

Sources & evidence

ORD record
ord-87a469ebc9384de7a85cd7f7d7e269de
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…