HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 67496215, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 67497428 | HCID 67497428 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 67496215 | HCID 67496215 | — |
Reaction Steps
To (R)-1-(1-ethyl-3-(pyridin-4-yl)-1H-pyrazol-5-ylamino)-1-oxo-3-phenylpropan-2-yl acetate (438 mg, 1157 μmol) was added K2CO3 (320 mg, 2315 μmol), followed by MeOH. After 1 hr, the reaction was completed by LC/MS. The reaction was concentrated and worked up with brine and 30% isopropanol in CHCl3. The crude material was purified by trituration with dichloromethane followed by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785468B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-f9645a33045643949bf2d5422fbf6032 |
| Source note | uspto-grants-2014_07 |