tert-Butyl 2-(5-(2-methylpyridin-4-yl)-3-nitropyridin-2-yloxy)acetate → tert-Butyl 2-(3-amino-5-(2-methylpyridin-4-yl)pyridin-2-yloxy)acetate

Participants

Reaction Steps

To a flask with 78.G (280 mg, 0.81 mmol) was added 112 mg 10% Pd/C. The reaction was purged with hydrogen and stirred under hydrogen for 4 hrs. After filtering through a pad of celite, silica gel purification afforded 78.H 134 mg (52%).

Provenance & Evidence