Dichloromethane → 7-amino-2-methyl-4-(pyrrolidin-1-ylcarbonyl)-2,3-dihydro-1H-isoindol-1-one
Reaction equation
[C:1]([N:5]([C:2](=[O:3])[O-:4])[c:9]1[c:10]2[c:14]([c:15]([C:18](=[O:19])[N:20]3[CH2:21][CH2:22][CH2:23][CH2:24]3)[cH:16][cH:17]1)[CH2:13][N:12]([CH3:25])[C:11]2=[O:26])([CH3:6])([CH3:7])[CH3:8].[Cl:34][CH2:35][Cl:36].[F:27][C:28]([F:29])([F:30])[C:31]([OH:32])=[O:33]>>[NH2:5][c:9]1[c:10]2[c:14]([c:15]([C:18](=[O:19])[N:20]3[CH2:21][CH2:22][CH2:23][CH2:24]3)[cH:16][cH:17]1)[CH2:13][N:12]([CH3:25])[C:11]2=[O:26]Participants
4
Sources & evidence
- ORD record
- ord-bc7ca9c49f20456db47a2b3a50535278
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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