反应详情

290 mg (1.02 mmol) 4-(2-carboxymethoxy-ethylamino)-3-nitro-benzoic acid in 100 ml dichloromethane are combined with 0.186 ml (2.55 mmol) thionyl chloride and 2 drops of DMF and refluxed for one day. After evaporation of the solution i. vac. it is evaporated with toluene and the residue is further reacted without any more purification.

1. temperaturerefluxed for one day
2. customAfter evaporation of the solution i
3. customit is evaporated with toluene
4. customthe residue is further reacted without any more purification