5-Chlorovaleryl chloride → Methyl 4-(5-chloro-pentanoyl-amino)-3-methoxy-benzoate

HRID 1629848노트

반응식

HRID 1629848 반응식
[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][C:3]=1[O:12][CH3:13].[Cl:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19](Cl)=[O:20]>C1COCC1>[Cl:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([NH:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][C:3]=1[O:12][CH3:13])=[O:20]

참가 물질

4

반응물 2

HCID 740895-Chlorovaleryl chlorideHCID 602411Methyl 4-amino-3-methoxybenzoate

생성물 1

HCID 67048137Methyl 4-(5-chloro-pentanoyl-amino)-3-methoxy-benzoate

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

Prepared analogously to Example 6a from methyl 4-amino-3-methoxy-benzoate and 5-chloro-pentanoic acid chloride in THF with TEA.

출처 및 근거

ORD 기록
ord-de2ed8a044a24679b13efe5926f0d3c2
출처 데이터셋
uspto-grants-2014_07
특허 번호
US08791103B2

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