Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1629848Generated: October 26, 2026

5-Chlorovaleryl chloride → Methyl 4-(5-chloro-pentanoyl-amino)-3-methoxy-benzoate

https://huagongshe.com/reaction/1629848

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chlorovaleryl chlorideHCID 74089—
ReactantMethyl 4-amino-3-methoxybenzoateHCID 602411—
SolventTetrahydrofuranHCID 8028—
ProductMethyl 4-(5-chloro-pentanoyl-amino)-3-methoxy-benzoateHCID 67048137—

Reaction Steps

Prepared analogously to Example 6a from methyl 4-amino-3-methoxy-benzoate and 5-chloro-pentanoic acid chloride in THF with TEA.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791103B2
Source datasetuspto-grants-2014_07
ORD IDord-de2ed8a044a24679b13efe5926f0d3c2
Source noteuspto-grants-2014_07