HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Triphenylphosphoranylidene)acetaldehyde → 3-(5-Bromopyridin-2-yl)prop-2-enal
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Triphenylphosphoranylidene)acetaldehyde | HCID 75051 | — |
| Reactant | 5-Bromopyridine-2-carbaldehyde | HCID 9877562 | — |
| Product | 3-(5-Bromopyridin-2-yl)prop-2-enal | HCID 86676730 | — |
Reaction Steps
818 mg of (triphenylphosphoranylidene)acetaldehyde and 500 mg of 5-bromopyridinecarbaldehyde are stirred at RT overnight. The volatile fractions are removed under reduced pressure, and the residue is purified by column chromatography (silica gel, MeOH:DCM=99:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791133B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-98d1666fa69e4f5cbd5826dff07f81d7 |
| Source note | uspto-grants-2014_07 |