HRID1630411

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID136360

1,3-Cyclohexanedione, 4,4-dimethyl-

C8H12O2

HCID86676729

未命名化合物

HCID131731700

未命名化合物

PRODUCTS

生成物

结构：CC1(C)CCC2=C(C1=O)C(/C=C/c1ccc(-c3cccc(F)c3)cn1)c1cn[nH]c1N2.NC(=O)CC1CC1

HCID137195794

未命名化合物

PROCEDURE

实验过程

The title compound is prepared according to procedure A from 50 mg of (E)-3-[5-(3-fluorophenyl)pyridin-2-yl]propenal, 31 mg of 4,4-dimethylcyclohexane-1,3-dione and 40 mg of 5-amino-1H-pyrazole-3-cyclopropylmethylcarboxamide.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d2e7f199afee4d3d832462eb0324b93b
来源数据集: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08791133B2
来源说明: uspto-grants-2014_07

反应 SMILES

[F:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:9]=[CH:10][C:11](/[CH:14]=[CH:15]/[CH:16]=O)=[N:12][CH:13]=2)[CH:5]=[CH:6][CH:7]=1.[CH3:18][C:19]1([CH3:27])[CH2:24][CH2:23][C:22](=O)[CH2:21][C:20]1=[O:26].[NH2:28][C:29]1[NH:33][N:32]=[CH:31][CH:30]=1.[CH2:34]1[CH:36]([CH2:37][C:38]([NH2:40])=[O:39])[CH2:35]1>>[F:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:9]=[CH:10][C:11](/[CH:14]=[CH:15]/[CH:16]3[C:21]4[C:20](=[O:26])[C:19]([CH3:27])([CH3:18])[CH2:24][CH2:23][C:22]=4[NH:28][C:29]4[NH:33][N:32]=[CH:31][C:30]3=4)=[N:12][CH:13]=2)[CH:5]=[CH:6][CH:7]=1.[CH2:35]1[CH:36]([CH2:37][C:38]([NH2:40])=[O:39])[CH2:34]1