HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Cyclohexanedione, 4,4-dimethyl- → 4-{(E)-2-[5-(3-Fluorophenyl)pyridin-2-yl]vinyl}-6,6-dimethyl-5-oxo-4,5,6,7,8,9-hexahydro-1H-pyrazolo[3,4-b]quinoline 3-cyclopropylmethylcarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Cyclohexanedione, 4,4-dimethyl- | HCID 136360 | — |
| Reactant | (E)-3-[5-(3-Fluorophenyl)pyridin-2-yl]propenal | HCID 86676729 | — |
| Reactant | 5-Amino-1H-pyrazole 3-cyclopropylmethylcarboxamide | HCID 131731700 | — |
| Product | 4-{(E)-2-[5-(3-Fluorophenyl)pyridin-2-yl]vinyl}-6,6-dimethyl-5-oxo-4,5,6,7,8,9-hexahydro-1H-pyrazolo[3,4-b]quinoline 3-cyclopropylmethylcarboxamide | HCID 137195794 | — |
Reaction Steps
The title compound is prepared according to procedure A from 50 mg of (E)-3-[5-(3-fluorophenyl)pyridin-2-yl]propenal, 31 mg of 4,4-dimethylcyclohexane-1,3-dione and 40 mg of 5-amino-1H-pyrazole-3-cyclopropylmethylcarboxamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791133B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-d2e7f199afee4d3d832462eb0324b93b |
| Source note | uspto-grants-2014_07 |