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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1631407Generated: November 3, 2026

(S)-1,1,1-trifluoropropan-2-amine → HCID 67500680, compound

https://huagongshe.com/reaction/1631407

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-1,1,1-trifluoropropan-2-amineHCID 10964447—
ReactantHCID 66847957HCID 66847957—
ProductHCID 67500680HCID 67500680—

Reaction Steps

Prepared according to the method of Example 212, Step F, using 54(2S,5R)-5-(5-fluoropyridin-3-yl)-2-(hydroxymethyl)-2-methylpyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (Example 219, Step F) and (S)-1,1,1-trifluoropropan-2-amine. The title compound was obtained as a white solid (5.4 mg, 31% yield). MS (apci) m/z=467.1 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791123B2
Source datasetuspto-grants-2014_07
ORD IDord-d8c88a21c185406688c23a53308a5de1
Source noteuspto-grants-2014_07