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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1631607Generated: November 2, 2026

2,4,5-Trifluoroaniline → HCID 136352201, compound

https://huagongshe.com/reaction/1631607

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,5-TrifluoroanilineHCID 94953—
ReactantSodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetateHCID 136041844—
ProductHCID 136352201HCID 13635220162.7%

Reaction Steps

The product is prepared according to the procedure described in Example 5, using 260 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 294 mg of 2,4,5-trifluoroaniline in place of the 2,4-difluoroaniline. 230 mg of 2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]-N-(2,4,5-trifluorophenyl)acetamide are obtained in the form of a white solid, the characteristics of which are the following:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08791255B2
Source datasetuspto-grants-2014_07
ORD IDord-554f9badc93d442788ab3e8cecd70927
Source noteuspto-grants-2014_07