4-Aminopyridine → HCID 68646785, compound

HRID 1631818Notes

Reaction equation

[C:1]([OH:20])(=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[NH2:21][C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1.C1CCC(N=C=NC2CCCCC2)CC1>>[N:25]1[CH:26]=[CH:27][C:22]([NH:21][C:1](=[O:20])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])=[CH:23][CH:24]=1

Participants

Reactant 3

HCID 17274-Aminopyridine

HCID 10868Dicyclohexylcarbodiimide

HCID 445639Oleic Acid

Product 1

HCID 68646785HCID 68646785, compoundYield 72%

Procedure

Reaction of oleic acid (1.00 g, 3.54 mmol) with 4-aminopyridine (0.33 g, 3.54 mmol) was conducted according to the general amide coupling procedure using DCC to obtain the product as a colorless liquid (0.91 g, 72%). EIMS m/z: 359 ([M]+).

Sources & evidence

ORD record: ord-6857d99b2b494a6e91c9b145cf8c552e
Source dataset: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08791275B2

Reaction notes

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