HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → (1-Benzyl-3,5-dimethyl-1H-pyrazol-4-yl)-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | (1-Benzyl-3,5-dimethyl-1H-pyrazol-4-yl)-acetic acid | HCID 1080743 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | (1-Benzyl-3,5-dimethyl-1H-pyrazol-4-yl)-acetic acid methyl ester | HCID 61381146 | — |
Reaction Steps
(1-Benzyl-3,5-dimethyl-1H-pyrazol-4-yl)-acetic acid (1.00 g, 4.1 mmol) was dissolved in 3N methanolic HCl (7.5 mL) and stirred at room temperature for 18 h. The reaction mixture was neutralized with aqueous NaHCO3 solution and extracted with dichloromethane. The organic layer was dried over MgSO4 and concentrated under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791272B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-aca3649779f649fdb54c7714a0f9b6cc |
| Source note | uspto-grants-2014_07 |