HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl 3-(3,5-dimethyl-1H-pyrazol-4-yl)propanoate → 3-[3,5-Dimethyl-1-(4-nitro-benzyl)-1H-pyrazol-4-yl]-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl 3-(3,5-dimethyl-1H-pyrazol-4-yl)propanoate | HCID 3410253 | — |
| Reactant | [3,5-Dimethyl-1-(4-nitro-benzyl)-1H-pyrazol-4-yl]-acetic acid methyl ester | HCID 66707610 | — |
| Product | 3-[3,5-Dimethyl-1-(4-nitro-benzyl)-1H-pyrazol-4-yl]-propionic acid ethyl ester | HCID 66707339 | — |
Reaction Steps
Intermediate 8.1.1 can be prepared according to the method described for intermediate 1.1.2, employing in the alkylation reaction 3-(3,5-dimethyl-1H-pyrazol-4-yl)-propionic acid ethyl ester (Akos, MFCD03834497) instead of (3,5-dimethyl-1H-pyrazol-4-yl)-acetic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791272B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-772c55c142eb4f0b845c8587def888ab |
| Source note | uspto-grants-2014_07 |