Sodium Methoxide → HCID 20443831, compound

HRID 1632185Notes

Reaction equation

HRID 1632185 reaction equation
Cl[C:2]1[C:7](=[O:8])[NH:6][C:5]2[O:9][CH2:10][C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=3[C:4]=2[CH:3]=1.C[O-:18].[Na+]>CO>[OH:18][C:2]1[C:7](=[O:8])[NH:6][C:5]2[O:9][CH2:10][C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=3[C:4]=2[CH:3]=1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 20443860HCID 20443860, compound

Product 1

HCID 20443831HCID 20443831, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Add 23.1 gm of 2-chloro-4,6-dihydro-3H[2]benzopyrano[3,4-b]pyridin-3-one to 300 ml of methanol containing 30 gm of sodium methoxide. Heat the system in a steel bomb at about 200° C. for 12 hours. Stop the reaction and remove the solvent by stripping. Treat the residue with water and then isolate the title compound.

Workup

  1. customthe reaction
  2. customremove the solvent
  3. additionTreat the residue with water

Sources & evidence

ORD record
ord-52ea9c7552af4cb7bbd58f53d918509f
Source dataset
uspto-grants-1984_10
Patent number
US04474786

Reaction notes

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