Propargylamine → HCID 178457560, compound

HRID 1632236Notes

Reaction equation

HRID 1632236 reaction equation
C(N)C#C.[CH2:5]([NH:8][C:9]([NH:13][CH2:14][CH2:15][S:16][CH2:17][C:18]1[N:19]=[C:20]([CH2:23][N:24]([CH3:26])[CH3:25])[S:21][CH:22]=1)=[N:10][C:11]#[N:12])[CH:6]=[CH2:7]>>[CH2:5]([NH:8][C:9]([NH:13][CH2:14][CH2:15][S:16][CH2:17][C:18]1[N:19]=[C:20]([CH2:23][N:24]([CH3:26])[CH3:25])[S:21][CH:22]=1)=[N:10][C:11]#[N:12])[C:6]#[CH:7]

Participants

3

Reactant 2

HCID 239041PropargylamineHCID 178457561HCID 178457561, compound

Product 1

HCID 178457560HCID 178457560, compound

Procedure

Following the above procedure, but substituting allylamine for propargylamine in the reaction with N-2-(2-dimethylaminomethyl-4-thiazolylmethylthio)ethyl-N'-cyanocarbamidothioate, N-allyl-N'-2-(2-dimethylaminomethyl-4-thiazolylmethylthio)ethyl-N"-cyanoguanidine was prepared. Yield=0.28 g from 600 mg of thioester.

Workup

  1. customwas prepared

Sources & evidence

ORD record
ord-74c9be332cd54fc1a6fcb1765a711794
Source dataset
uspto-grants-1984_10
Patent number
US04474794

Reaction notes

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